NEWS
May 2025
Warm welcome to Dr. Dhanunjay Mukhi, our new Research Associate! Dhanunjay will investigate the role of replication-independent histone variants in regulating the genome of non-dividing cells and explore their potential contribution to epigenomic changes during mammalian aging.
APRIL 2025
Andrey has been invited to serve as Guest Editor for a JoVE special issue on “Mass Spectrometry-Based Approaches in Chromatin Biology”. We welcome submissions reporting methods for quantitative analysis of histone protein and nucleic acid modifications, chromatin-associated factors, and … .READ MORE.
February 2025
The Tvardovskiy Lab is getting ready to install the Orbitrap Astral — a state-of-the-art mass spectrometer that combines the high-resolution Orbitrap and the novel Asymmetric Track Lossless (Astral) analyzer. We're excited to explore its capabilities for quantitative analysis of nuclear proteins and histone modifications. Stay tuned!
JULY 2024
Two research highlights featuring .MARCS. - the Modification Atlas of Regulation by Chromatin States - are out in Nature Reviews Genetics (link) and Epigenomics (link). We developed MARCS as an interactive web tool to communicate our findings, offering actionable insights into chromatin regulatory circuits. .READ MORE.
MAY 2024
Andrey is thrilled to announce that he will be joining the University of Pennsylvania as an Assistant Professor in the Department of Biochemistry and Biophysics and a core member of the Epigenetics Institute in January 2025.